Contraindicated (one)pentobarbital decreases amounts of vandetanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay away from coadministration with potent CYP3A4 inducers; these medications minimize publicity to vandetanib by around 40%.

pentobarbital will reduce the extent or effect of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

pentobarbital will decrease the level or impact of bexarotene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Observe Carefully (1)pentobarbital will minimize the extent or effect of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Loss of, or lowered response to tofacitinib may possibly occur when coadministered with powerful CYP3A4 inducers

Observe Carefully (1)pentobarbital will reduce the extent or effect of fentanyl intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to the minimize in fentanyl plasma concentrations, deficiency of efficacy or, probably, improvement of the withdrawal syndrome in the individual who has made physical dependence to fentanyl. After halting a CYP3A4 inducer, as the consequences on the inducer decline, the fentanyl plasma concentration will improve which more info could maximize or prolong both of those the therapeutic and adverse outcomes.

pentobarbital will lessen the extent or result of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will minimize the extent or effect of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the extent or influence of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Steer clear of coadministration of lefamulin with powerful or moderate CYP3A inducers Except the reward outweighs dangers. Observe for lowered efficacy.

pentobarbital will lessen the extent or influence of conjugated estrogens, vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

pentobarbital will lessen the level or result of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.

pentobarbital will minimize the level or outcome of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.

pentobarbital will lessen the extent or result of alosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.

pentobarbital will lessen the extent or outcome of darunavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will reduce the extent or outcome of dasatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.